Hashimoto’s Thyroiditis
Hashimoto’s Thyroiditis (Hashi’s) is the most common cause of
hypothyroidism. It is autoimmune in nature in that the body attacks its
own thyroid gland. Early on, when there is destruction of the thyroid,
the release of thyroid hormone can temporarily cause a hyper state.
When enough destruction has occurred and the thyroid gland can
make only a small amount of hormone, the result is hypothyroidism.
Anti thyroglobulin antibodies and/or thyroid peroxidase antibodies are
usually present in blood testing among those suffering from Hashi's.
Although doctors generally only make a diagnosis of Hashi’s when
these antibodies are above range, many in the forward-thinking
community recognize that any antibodies indicates Hashi’s. If
antibodies are low, it usually means the thyroid is not currently under
attack.
Thyroid antibody testing listed here
Hyperthyroid
There are a number of conditions causing an overactive or hyper
thyroid. If blood testing results in a free T4 level near the top of, or
above, its range, and higher in its range than FT3 is in its – unless it
can be explained with high doses of T4-containing thyroid medication –
it may point to an overactive thyroid or Graves Disease.
Grave’s Disease is an autoimmune condition in which antibodies signal
the thyroid gland to make too much T4. Typically there is elevation of
Thyroid stimulating immuneglobulin. Levels of 130 or higher are usually
considered evidence of Grave’s Disease, but any antibodies may
indicate a problem.
With hyperactive thyroid, thyroid stimulating hormone is usually very
low but can appear normal or even elevated. Anti thyroglobulin
antibodies and/or thyroid peroxidase antibodies and anti-nuclear
antibody can also be elevated in Graves’ disease. Graves is frequently
accompanied by goiter (enlarged thyroid). It is more common in women
than men and most likely occurs in people in the 30s or 40s.
Symptoms of hyperthyroidism may include being nervous, irritable,
weak or tired, excessive sweating, more bowel movements than usual,
high heart rate, palpitations, weight loss, itchy skin and shakiness.
Hyperthyroidism is frequently treated with beta blockers, to reduce the
symptoms, and other drugs such as methimazole and propylthiouracil
(PTU), which interfere with the thyroid's ability to produce hormones. In
mild conditions, it is possible that exogenous T3-only medication will
suppress the thyroid activity and resolve the hyperthyroid condition.
Radioactive iodine is often used to destroy thyroid tissue as a
treatment for hypertyroidism or Graves. It is administered in capsule
form on a one- time basis and directly radiates and destroys thyroid
tissues. The majority of patients undergoing treatment with radioactive
iodine eventually become hypothyroid. Radioactive iodine is the
preferred initial therapy for the hyperthyroidism of Graves' disease in
North America while antithyroid drugs are used as the first line of
treatment in most of the rest of the world.
Many doctors are anxious to remove a hyperactive thyroid with surgery
or destroy it with radioactive iodine. Forward-thinking healthcare
professionals recognize this should be only a last resort. When
hyperthyroidism is due to a hot nodule in an accessible area of only
one thyroid lobe, surgery creates less long-term issues.
Hyperthyroid testing listed here
Subacute thyroiditis
Subacute thyroiditis can temporarily cause a hyperthyroid state. The
thyroid gland becomes inflammed and swollen causing excess thyroid
hormone to be released (thyroid dump). It is thought to be caused by a
virus sometimes following an upper respiratory infection. It may be
treated with anti-inflammatory drugs such as aspirin or ibuprofen. If the
heart rate is excessively high, a beta blocker may be given to slow the
heart rate. The hyper condition will frequently be followed with a hypo
state, until the thyroid inflammation improves and the thyroid begins
producing hormone again. Subacute thyroiditis generally resolves itself
spontaneously within a few months.
Toxic multinodular goiter
This is a condition in which the thyroid gland contains multiple lumps or
nodules that are overactive and produce excess thyroid hormones.
They are sometimes referred to as "hot" nodules.
Thyroid storm
Thyroid storm is a severe, life-threatening condition caused by an
extreme excess of thyroid hormone. It can be caused by
over-replacement of thyroid hormones or discontinuing medications
taken to treat hyperthyroidism. Symptoms of thyroid storm can include
fever (potentially as high as 106 degrees F), racing pulse,
nausea,vomiting, diarrhea, irregular heart beat, confusion, and
weakness. Thyroid storm may lead to heart failure and requires
emergency medical treatment.